Jyotirmoy Chatterjee


Research Statement

Knowledge the Continuum’in understanding ‘homeostatic thresholds of life’ in the context of  health & disease. Life is manifested in ‘multiple modes and scales’ to form ‘complex patterns’Nourishing logically  ‘Knowledge the Continuum’ with all sorts of available domain knowledge (applied, abstract, intuitive) through path of multi-disciplinary integration. Living systems become more complex essentially through the trauma connotation path. Transformation of trauma into intelligence essentially entails the embodiment of evolving systemic consciousness from the interplay of co-occurring cooperation and competition within certain thresholds which are irreversibly impaired in non-healing diseases.  Systemically evolved consciousness may be comprehended in depth  through more interaction with ‘mathematical abstractions’ and ‘astronomical studies’. This understanding about health and disease can be utilized to explore early diagnostic/ theranostic signatures and in developing effective therapeutic strategy /tools as well as for disease prevention. Overall  this approach cultivates both fundamental and translational dimensions in medical/biomedical research.Enriched with this concept our interdisciplinary research work in the field of early diagnosis of malignant potetiality of pre-cancer/ cancer, healing of  diabetic/non-healing wounds, regenerative medicines, honey as a systemic healer and Yoga-Naturopathy.In the research activity it involves in vitro and in vivo studies through employing multimodal molecular/spectroscopic/ microscopic/sub-surface/ transbody imaging and analysis, regeneratve medicine approaches with special application of honey-biomaterial based constructs/film/gels.


  • 1 Oral Pre-cancer Therapeutic Patch Dev.
  • 2 Wound Healing & Honey
  • 3 Stem cells Diffe. & Honey based Matrix
  • 4 Multi-modal Imaging on Oral cancer Diag
  • 5 Lung Cancer & Diabetic Retinopathy Diag


  • Nag M. K., Chatterjee S. , Sadhu A. K., Chatterjee J. , Ghosh N., Computer-assisted Delineation of Hematoma from CT Volume using Autoencoder and Chan Vese Model, Intl. Journal of Computer Assisted Radiology and Surgery, 2020
  • Basu S., Chaudhary A. , Chowdhury P. , Karmakar D. , Basu K. , Karmakar D. , Chatterjee J. , Sengupta S., Evaluating the role of hsa-miR-200c in reversing the epithelial to mesenchymal transition in prostate cancer, Gene, 730, 2020
  • Khan T., Das R. S., Arya B. K., Chaudhary A. , Chatterjee J. , Bhattacharya S. D., Impact of pneumococcal conjugate vaccine on the carriage density of Streptococcus pneumoniae and Staphylococcus aureus in children living with HIV: a nested case-control study, Human Vaccines & Immunotherapeutics, 2020
  • Chatterjee R., Chatterjee J., ROS and oncogenesis with special reference to EMT and stemness, European Journal of Cell Biology, 99, 2020
  • Mandal M., Rajput M. , Anura A. , Pathak T. , Chatterjee J., Regulation of epithelial mesenchymal transition under compliant polydimethylsiloxane substrate, Biophysical Society 63rd Annual Meeting, 2019
  • Maity M., Gantait K. , Mukherjee A. , Chatterjee J., Visible Spectrum-based Classification of Malaria Blood Samples on Handheld Spectrometer, 2019 IEEE International Instrumentation and Measurement Technology Conference (I2MTC), Auckland, New Zealand, 1-5, 2019
  • Nawn D., Chatterjee S. , Anura A. , Bag S. , Chakraborty D. , Pal M. , Paul R. R., Chatterjee J., Elucidation of Differential Nano-Textural Attributes for Normal Oral Mucosa and Pre-Cancer, Microscopy and Microanalysis, 1-10, 2019
  • Dey S., Ray A. , Maity, N. C., Banerjee P. , Chatterjee J. , Maity S. P., Roychowdhury A. , Barui A., Precise segmentation & Classification of epithelial rete-pegs signature in assessing lower limb healing progression, J of Medical & Biological Engineering, 151-162, 2019
  • Mandal M., Rajput M. , Anura A. , Pathak T. , Chatterjee J., Regulation of Epithelial Mesenchymal Transition under Compliant Polydimethylsiloxane Substrate, Biophysical Journal, 2019
  • Nag R., Pal M. , Paul R. R., Chatterjee J. , Das R. K., Segmentation and analysis of surface characteristics of oral tissues obtained by scanning electron microscopy to differentiate normal and oral precancerous condition, Tissue and Cell, 82-87, 2019
  • Chaudhary A., Bag S. , Banerjee P. , Chatterjee J., Wound healing efficacy of Jamun honey in diabetic mice model through reepithelialization, collagen deposition and angiogenesis, Journal of Traditional and Complementary Medicine, 2019
  • Muley S., Ghosh B. , Chatterjee J, Automated hidden peak extraction in Raman spectra for fibrotic skin tissues, IEEE EMBC, 2018
  • Nag M. K., Vupputuri A. , Chatterjee S. , Sadha A. K., Chatterjee J. , Ghosh N., Delineation of Hemorrhagic mass from CT volume, AHFE 2018, 130-138, 2018
  • Nag R., Raza H. , Kumar S. , Seal R. , Banerjee A. , Paul R. R., Pal M. , Chatterjee J. , Das R. K., Detection and analysis of abnormal nuclear changes in oral cytological smears by Papanicolaou staining, Cytopathology, 112-114, 2018
  • Anura ., Kazi A. , Pal M. , Paul R. R., Sengupta S. , Chatterjee J., Endorsing cellular competitiveness in aberrant epithelium of oral sub-mucous fibrosis progression: neighborhood analysis of immunohistochemical attributes, Histochemistry & Cell Biology, 150, 61-75, 2018
  • Bag S., Dutta D. , Chaudhary A. , Singh B. C., Pal M. , Ray A. K., Banerjee R. , Paul R. R., Basak A. , Das A. K., Chatterjee J, Identification of -enolase as a prognostic and diagnostic precancer biomarker in oral submucous fibrosis, J. Clin. Path., 228-238, 2018
  • Sarkar S., Chaudhary A. , Saha . K., Das A. K., Chatterjee J., Modulation of collagen population under honey assisted wound healing in diabetic rat, Wound Medicine, 20, 7-17, 2018
  • Sarkar A., Sadhu A. , Sengupta S. , Basu Thakur S. , Mukherjee A. , Chatterjee J., Fourier transform infra red spectroscopy based spectral biomarker identification: Applications in classifying lung cancer subtypes, 253rd ACS National Meeting in San Francisco, 2017
  • Sarkar A., Sengupta S. , Mukherjee A. , Chatterjee J., Fourier transform infra-red spectroscopic signatures for lung cells' epithelial mesenchymal transition: A preliminary report, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 809-816, 2017
  • Chaudhary A., Bag S. , Banerjee P. , Chatterjee J., Honey Extracted Polyphenolics Reduces Experimental Hypoxia in Human Keartinocytes Culture, Journal of Agricultural and Food Chemistry, 2017
  • Bag S., Dutta D. , Chaudhary A. , Sing B. C., Pal M. , Ray A. K., Banerjee R. , Paul R. R., Basak A. , Das A. K., Chatterjee J., Identification of -enolase as a prognostic and diagnostic precancer biomarker in oral sub-mucous fibrosis, Journal of Clinical Pathology, 2017
  • Anura A., Das D. , Pal M. , Pal R. R., Das S. , Chatterjee J., Nanomechanical Signatures of Oral Submucous Fibrosis in Sub-epithelial Connective Tissue, Journal of the Mechanical Behavior of Biomedical Materials, 65, 705-715, 2017
  • Sarkar A., Sadhu A. , Basu Thakur S. , Sengupta S. , Mukherjee A. , Chatterjee J., Multimodal characterization of radiologically detectable lung lesions, 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2016
  • Das K., Guha Roy A. , Ghosh B. , Chatterjee J. , Sheet D., Simulation of B-mode Optical Coherence Tomography from Histology, IEEE Int. Symp. on Biomedical Imaging (ISBI), 2016
  • Anura A., Das D. , Pal M. , Paul R. R., Das S. , Chatterjee J., Unrevealing nanomechanical signatures of epithelial and connective tissue of oral submucous fibrosis, Biophysical Society Conference: Mechanobiology of Disease, 2016
  • Banerjee S., Chatterjee J., Food Engineering Emerging Issues, Modeling, and Applications, Phytochemicals, Functional Food, and Nutraceuticals for Oral Cancer Chemoprevention, 165-188, 2016
  • Banerjee S., A. , Chakraborty D. , Giri A. , Ghosh R. , Chatterjee J., Application of fuzzy consensus for oral pre-cancer and cancer susceptibility assessment, Egyptian Informatics Journal, 17, 251-263, 2016
  • Karri S., Chakraborty D. , Chatterjee J., Learning layer-specific edges for segmenting retinal layers with large deformations, Biomedical Optics Express, 2888-2901, 2016
  • S Banerjee, M Pal, J Chakrabarty, C Petibois, R Rashmi Paul, A Giri, J Chatterjee, Fourier-transform-infrared-spectroscopy based spectral-biomarker selection towards optimum diagnostic differentiation of oral leukoplakia and cancer, Analytical and bioanalytical chemistry, 7935-7943, 2015
  • A., Khare R. , Dhara S. , Banerjee P. , Chatterjee J., Ex vivo bio-compatibility of honey-alginate fibrous matrix for HaCaT and 3T3 with prime molecular expressions, J Mater Sci Mater Med, 25, 2659-2667, 2014
  • Das R. K., Pal M. , Barui A. , Paul R. R., Chakraborty C. , Ray A. K., Chatterjee J, ApoTome to Visualize p63 and E-Cadherin in Oral Pre-cancer, Biotechnology Journal, 7, 602-607, 2012
  • Dutta P., Dhara S. , Chatterjee J., Hydrogels and electrospun nanofibrous scaffolds of N- methylene phosphonic chitosan as bioinspired osteoconductive materials for bone grafting, Carbohydrate Polymers, 87, 1354-1362, 2011
  • A Barui, P Banerjee, R Patra, RK Das, S Dhara, PK Dutta, J Chatterjee, Swept-source optical coherence tomography of lower limb wound healing with histopathological correlation, Journal of Biomedical Optics, 2011
  • Sheet D., Chatterjee J. , Garud H., Feature Usability Index and Optimal Feature Subset Selection, Int. J of Computer Applications, 12, 29-36, 2010
  • Sheet D., Garud H. , Suveer A. , Mahadevappa M. , Chatterjee J., Brightness Preserving Dynamic Fuzzy Histogram Equalization, IEEE Transactions on Consumer Electronics, 2475-2480, 2010


  • Investigating the Role of Microtubule Regulations by Fidgetin in Epithelial-Mesenchymal Transition and Cancer Cell Motility
  • Developing Functional Skin Construct with Embedded Pericytes: Potential for Vascularization
  • Revealing Structural and Bio-Molecular Basis of Ayurvedic Biology in Diabetic Wound Healing under Characteristics Madhu (Honey) and Ghruta (Cow Ghee)
  • Stem Cell Conductive Honey-Biomaterial Blended Regenerative Healing Scaffold (ICG_2017)
  • Multimodal Evaluation of Umbilical Cord Mesenchymal Stem Cells and Their Trans-differentiation into Epithelial Ceils Under Honey Based Bio-matrix
  • Ultra Low Cost Honey - Silk Fibroin Therapeutic Patches for Control of Oral Cancer Recurrence
  • Integrated application of multimodal optical coherence tomography and multispectral imaging for spatio-functional characterization of skin towards in vivo histology (SGIRG)
  • Integrated application of multimodal optical coherence tomography and multispectral imaging for spatio-functional characterization of skin towards in vivo histology
  • Noninvasive characterization of healing and nonhealing wounds and development of honey-biomaterial and stem cell based wound therapy
  • Multimodal and multi-scale imaging for early diagnosis and interventional management of oral pre-cancers and cancer
  • Structural and molecular characterization of cutaneous cell behaviour under varied physico-chemical ambience towards improving skin tissue engineering practices.
  • An Electrochemical Sensor Based Handheld Potentiostat to Measure Urea/Creatinine Ratio in Blood and Urine
  • Signals & systems for life science


  • Chairman, Ethical Comm. GNIDSR


  • Tea based hydrogel preparation and application thereof
  • A Novel Function for Attenuation Coefficient Mapping of Swept Source - Optical Coherence Tomograms (SS-OCT) of Skin and Oral Mucosa
  • Adaptive weighted-local-difference order statistics filters : Granted

Research Group

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Anurup Mukhopadhyay
Research Scholars
Bio-material fabric for healing applications
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Ayan Gope
Research Scholars
Cell Bio-matrix Interaction in Healing
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Biswajoy Ghosh
Research Scholars
Correlated Multi-modal Imaging and Analysis of Oral Pre-cancer/ Cancer
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Debaleena Nawn
Research Scholars
Multimodal Characterization of Wounds
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Dhruba Dhar
Research Scholars
Nanomaterial based molecular imaging and microfluidics
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Kausik Das
Research Scholars
Computational imaging and machine learning
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Maitreya Maity
Research Scholars
Medical Image Analysis & Pattern Recognition
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Mousumi Mandal
Research Scholars
Interface between cancer and regeneration
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Neha Sharma
Research Scholars
Multi modal characterisation of tissues and cells in wound healing and cancer as well as under interventions
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Niladri Garai
Research Scholars
Computational Multimodal Imaging of Tissues in Health and Disease
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R. Siva Kumar Raju
Research Scholars
Cancer Diagnostic