Research

• 1 Cancer Drug Discovery
• 2 Chemoresistance
• 3 Cell Signaling
• 4 Cancer Stem Cell

Teaching

Publications

• Rajesh Y., Biswas A. , Banik P. , Pal I. , Das S. , Borkar S. A., Sardana H. , Saha A. , Das S. K., Emdad L. , Fisher P. B., Mandal M., Transcriptional regulation of HSPB1 by Friend leukemia integration-1 factor modulates radiation and temozolomide resistance in glioblastoma, Oncotarget, 11, 1097-1108, 2020
• Ganguly S., Das P. , Das T. K., Ghosh S. , Das S. , Bose M. , Mandal M. , Das A. K., Das N. C., Acoustic cavitation assisted destratified clay tactoid reinforced in situ elastomer-mimetic semi-IPN hydrogel for catalytic and bactericidal application, Ultrasonics Sonochemistry, 2020
• Rajesh Y., Biswas A. , Kumar U. , Banerjee I. , Das S. , Maji S. , Das S. K., Emdad L. , Cavenee W. K., Mandal M. , Fisher P. B., Lumefantrine, an Antimalarial Drug, Reverses Radiation and Temozolomide Resistance in Glioblastoma, Proceedings of the National Academy of Sciences, 11, 12324-12331, 2020
• Bharadwaj D., Mandal M., Senescence in Polyploid Giant Cancer Cells: A Road That Leads to Chemoresistance, Cytokine Growth Factor Rev, 52, 68-74, 2020
• Rajesh Y., Kumar U. , Mandal M., Heat Shock Proteins in Neuroscience, by Rajesh Y., Kumar U. , Mandal M., Therapeutic aspects of heat shock proteins in glioma: Cementing the crevasses between bench and bedside, 2019
• Pradeep N. D., Chaudhuri A. , Yarra . , Jena . , Behara . , Mandal M., Real-time monitoring of photo-activated hydrogen persulfide donor for biological entities, Org. Biomol. Chem, 2019
• Rajesh Y., A B. , U K. , S D. , Banerjee I. , Banik P. , Bharti R. , Nayak S. , Ghosh S. K., Mandal M, Targeting NFE2L2, a transcription factor upstream of MMP-2: A potential therapeutic strategy for temozolomide resistant glioblastoma, Biochem Pharmacology, 1-16, 2019
• Mandal S. M., Sinha T. K., Katiyar A. K., Das S. , Mandal M. , Ghosh S., Existence of Carbon Nanodots in Human Blood, J Nanosci Nanotechnol, 6961-6964, 2019
• Das S., Jena B. C., Mundre S. , Parekh A. , Rajesh Y. , Mandal M, Integrin 1 regulates doxorubicin resistance in breast cancer via FAK-mediated activation of ERK1 pathway, Annual meeting of American Association of Cancer Research, 2018
• Jena B. C., Das C. K., Bharadwaj, D. , Das S. , Parekh A. , Mandal M., Tamoxifen resistance breast cancer induces mesenchymal phenotype in fibroblasts through TGF 1 signalling, European Congress on Biotechnology, 2018
• Bharadwaj, D., Parekh A. , Das S. , Jena B. C., Mandal M., Polyploid giant cancer cells induce growth arrest and cytoskeletal rearrangement in breast cancer cells, European Congress on Biotechnology, 2018
• Das C. K., Jena B. C., Das S. , Parekh A. , Dey G. , Bharti R. , Bharadwaj D. , Mandal M., Parkin-mediated mitophagy regulates 5-fluorouracil-induced chemoresistance in breast cancer, AACR Annual Conference 2018 at Chicago, USA, 1348-1348, 2018
• Biswas A., Yetirajam R. , Das S. , Parekh A. , Mandal M., Targeting ECM via stress associated regulation: A potential therapeutic avenue for overcoming temozolamide resistance in glioblastoma, European Congress on Biotechnology, 2018
• Biswas S., Rajesh Y. , Barman S. , Bera M. , Paul A. , Mandal M. , Pradeep N. D., A dual-analyte probe: hypoxia activated nitric oxide detection with phototriggered drug release ability, Chem Commun, 7940-7943, 2018
• Sau M. C., Rajesh Y. , Mandal M. , Bhattacharjee M., Copper Catalyzed Regioselective N Alkynylation of Pyrazoles and Evaluation of the Anticancer Activity of Ethynyl Pyrazoles, Chemistryselect, 3511-3515, 2018
• Sohail S., Jaffery J. A., Biswas K., Jigsaw electrode design for electrowetting devices, Micro & Nano Letters, 1046-4059, 2018
• Rajesh Y., Mandal M., Proteases in Physiology and Pathology, Regulation of extracellular matrix remodeling and epithelial-mesenchymal transition by matrix metalloproteinases: decisive candidates in tumor progression, 154-159, 2017
• Rajesh Y., Biswas A. , Mandal M., Glioma progression through the prism of heat shock protein mediated extracellular matrix remodeling and epithelial to mesenchymal transition, Exp Cell Res., 2017
• Sarkar S., Konar S. , Nagaprasad, P. , Shashi Rajputl S. , Kumar B. , Rao R. R., Mahanty A. (., Pathak, Paul B. Fisher, P. B., Mandal M, Micellear Gold Nanoparticles as Delivery Vehicles for Dual Tyrosine Kinase Inhibitor ZD6474 for Metastatic Breast Cancer Treatment, Langmuir, 7649-7659, 2017
• Biswas G., Jena B. C., Maiti S. , Samanta P. , Mandal M. , Dhara D., Photoresponsive Block Copolymer Prodrug Nanoparticles as Delivery Vehicle for Single and Dual Anticancer Drugs, ACS Omega, 6677-6690, 2017
• Sapru S., Mandal M. , Ghosh A. K., Kundu S. C., Antibacterial nanofibrous matrices of non-mulberry silk sericin for wound repair, TERMIS-AM Annual conference and Exhibition, 2016
• Das D., Anura A. , Das S. , Mandal M. , Das S, AFM based Biomechanical Characterization for Assessment of Cancer Aggressiveness, Biophysical Society Conference: Mechanobiology of Disease, 2016
• Naskar D., Sapru S. , Li Z. , Yang X. , Mandal M. , Ghosh A. K., Kundu S. C., Non-mulberry silk fibroin based nerve guide biomaterials for neural tissue engineering, European chapter meeting TERMIS, Upsala, Sweden, 2016
• Bhutia S. K., Behera B. , Mandal M. , Maiti T. K, Abrus agglutinin is a potent anti-proliferative and anti-angiogenic agent in human breast cancer, Int. J of Cancer, 457-466, 2016
• Kalita H., Kumar B. P., Konar S. , Tantubay S. , Mahto M. K., Mandal M. , Pathak A., Sonochemically synthesized biocompatible zirconium phosphate nanoparticles for pH sensitive drug delivery application, Materials Science and Engg:C (Mater. for Bio. Appl.), 84-91, 2016
• Banerjee K., Banerjee S. , Mandal M., Biological and Pharmaceutical Applications of Nanomaterials. Liposomes as a drug delivery system, Liposomes as a drug delivery system, 2015
• Banerjee K., Banerjee S. , Das S. , Mandal M., Probing the potential of apigenin liposomes in enhancing bacterial membrane perturbation and integrity loss, J Colloid Interface Sci., 48-59, 2015
• Karthik, S., Kumar B. N., Gangopadhyay M. , Mandal M. , Pradeep N. D., A targeted, image-guided and dually locked photoresponsive drug delivery system, Journal of Materials Chemistry B, 728-732, 2015
• Basak K., Dey G. , Sheet D. , Mahadevappa M. , Mandal M. , Dutta P. K, Probabilistic graphical modeling of speckle statistics in laser speckle contrast imaging for noninvasive and label-free retinal angiography, Conf Proc IEEE Eng Med Biol Soc, 2015
• Dey G., Bharti R. , Sen R. , Mandal M., Microbial amphiphiles: a class of promising new-generation anticancer agents, , 136-146, 2015
• Parida S., Mandal M., Anti-Angiogenesis Drug Discovery and Development, Mechanism of Controlling Blood Vessel Growth and Development and Identification of Therapeutics Against Pathological Angiogenesis, 2014
• Mahata D., Mandal S. M., Mandal M. , Nag A. , Nando G. B., Self-assembled cardanol azo derivatives as antifungal agent with chitin-binding ability, Int J Biol Macromol, 5-11, 2014
• Choudhury H., Gorain B. , Dey G. , Mandal M. , Pal T. K., Improvement of cellular uptake, in vitro antitumor activity and sustained release profile with increased bioavailability from a nanoemulsion platform, Int J Pharm., 131-143, 2014
• Sen K., Mandal M., Second generation liposomal cancer therapeutics: transition from laboratory to clinic, Int J Pharm, 28-43, 2013
• Rajput S., Kumar B. N., Sarkar S. , Fisher P. B., Mandal M., Targeted apoptotic effects of thymoquinone and tamoxifen on XIAP mediated Akt regulation in breast cancer, Plos One, 2013
• Rajput S., Mandal M., Antitumor promoting potential of selected phytochemicals derived from spices: a review, Eur J Cancer Prev, 205-215, 2012
• Sarkar S., Mandal M., Breast Cancer: Classification Based on Molecular Etiology Influencing Prognosis and Prediction, Breast Cancer: Classification Based on Molecular Etiology Influencing Prognosis and Prediction, 69-84, 2011
• Sarkar S., Mazumdar A. , Dash R. , Sarkar D. , Fisher P. B., Mandal M., ZD6474 enhances paclitaxel antiproliferative and apoptotic effects in breast carcinoma cells, J Cell Physiol, 375-384, 2011
• Thalukder S., Mandal M. , Kundu S. C, Engineered silk fibroin protein 3D matrices for in vitro tumor model, Biomaterials, 2011
• Jaganathan S. K., Mandal S. M., Jana S. K., Mandal M., Studies on the phenolic profiling, anti-oxidant and cytotoxic activity of Indian honey: in vitro evaluation, Nat Prod Res, 24, 2010
• Mandal S. M., Mandal M. , Das A. K., Pati B. R., Ghosh A. K., Stimulation of indoleacetic acid production in a Rhizobium isolate of Vigna mungo, Arch Microbio, 389-393, 2009
• Mandal S. M., Mandal M. , Pati B. R, Proteomics view of a Rhizobium isolate response to arsenite [As(III)] stress, Acta Microbiol Immunol Hung, 157-167, 2009
• Kupferman M. E., Mandal M, Therapeutic suppression of constitutive and inducible JAK\STAT activation in head and neck squamous cell carcinoma, J Exp Ther Oncol, 117-127, 2009
• Majumder G. C., Mandal M. , Banerjee S, In Recent Advances in Animal Science Research, A Novel Sperm Motility-promoting Protein from Blood Serum and Its Applied Potential, 61-67, 2001
• Majumder G. C., Roy N. , Mandal M. , Banerjee S., Anti-sticking factors and regulators of sperm motility, Anti-sticking factors and regulators of sperm motility, 193-210, 1992

Projects

• Signals & systems for life science
• Development of dense and porous Titanium components via powder metallurgy route for biomedical applications
• System for Cyto - Reduction of Circulating Cancer Cells from Blood and a Method Thereof
• Pilot Scale Study on Local Inhabitants Reduction of Fear to AAI Programme as Par Demand of Local Administration
• Combining Metformin and Metronomic Liposomal Chemotherapeutic Formulation for Effective Management of Multiple Cancers
• Dealing with the cancer of Cervix: Enhancing the efficacy of ionizing radiation with gold nanoparticle
• Engineered silk matrices for optimization of in vitro 3 D tumour model
• Delivery of drugs and cells to the cornea using silk protein-A novel therapeutic approach
• Natural silk protein based modification of Orthopedic implant to improve osteogenesis and osseo-integration
• Unraveling cancer transformation and progression through biological, electro-mechanical and computational techniques
• Involvement of functional single nucleotide polymorphisms (SNP) of matrix metalloproteinase (MMP) gene promoters in the cell type specific regulation of human MMPs: intrinsic genetic characteristics in cancer cell progression

Awards

• FAScT
• FNA
• FNASc
• FNSc
• J C Bose National Fellow

Patents

• Selective leukapheresis. System for cytoreduction of circulating cancer cells from blood and a method there of
• Anti Bacterial Hydrogel Composition and Application Thereof
• A process for the purification of a new motility-promoting protein from buffalo serum: A slaughter house waste

Research Group

Angana Biswas

Ph.D

Research Scholars

Cancer Biology

Bikash Chandra Jena

Ph.D

Research Scholars

Cancer Biology

Deblina Bharadwaj

Ph.D

Research Scholars

Cancer Biology

Madhurima Mandal

Ph.D

Research Scholars

Cancer Biology

Moumita Kundu

Ph.D

Research Scholars

Cancer Biology

Payel Banik

Ph.D

Research Scholars

Cancer Biology

Pritam Kumar Roy

Ph.D

Research Scholars

Cancer Biology

Ranabir Majumder

Ph.D

Research Scholars

Validation of phytomedicine on chronic disease therapy

Shreya Banerjee

Ph.D

Research Scholars

Cancer Biology

Subhayan Das

Ph.D

Research Scholars

Cancer Biology